Description of a new experimental model skin flap for studying skin viability in rats.

نویسندگان

  • Cristina Pires Camargo
  • Nelson Fontana Margarido
  • Eduardo Guandelini
  • Guilherme Alexandre Barrucci Vieira
  • Alfredo Luiz Jacomo
  • Rolf Gemperli
چکیده

PURPOSE To describe a new experimental flap for studying skin viability in rats. METHODS Twenty male Wistar rats weighing between 250-300g were divided into two groups: group A - McFarlane technique, a 4 x 10cm flap was used (McFarlane); and in group B modified McFarlane technique, a 3 x 10cm flap was used. Seven days later, the animals were sacrificed and the area of necrosis was evaluated in both groups. RESULTS Group A presented necrosis in 3% of the total area of the flap (CI: 0.01-0.05), Group B presented necrosis in 37% of the total area of the flap (CI: 0.29-0.46), (p<0.001). CONCLUSION The modified McFarlane flap presented a larger area of necrosis and could be an adequate experimental model of skin flap viability.

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عنوان ژورنال:
  • Acta cirurgica brasileira

دوره 29 3  شماره 

صفحات  -

تاریخ انتشار 2014